Plus: The US has frozen green cards for Microsoft and other IT firms. We're putting too much faith in AI's ability to say no Today's AI models are trained to refuse a vast number of prompts. If you ask your chatbot how to poison a colleague or how to tie a noose, chances are it'll turn you down. But refusal fails, sometimes horrifically. Some people are attempting to use AI to hone biological pathogens and build autonomous drone swarms. Sooner or later, failed refusals may result in global calamity.

Plus: OpenAI has released 377 new math findings, further rattling the field. Popular weight-loss drugs may do more than help people shed pounds. They might also slow the aging process. Drugmakers Eli Lilly and Novo Nordisk say patients taking their GLP-1 drugs age less quickly, according to molecular "aging clocks" that track changes in DNA or levels of key proteins. The findings add to speculation that GLP-1 drugs could be acting on basic causes of aging and might be true longevity treatments. But how much can we read into these results?

In a series of interviews, we're meeting some of the PhD students that were selected to take part in the Doctoral Consortium at the International Joint Conference on Artificial Intelligence and the 29th European Conference on Artificial Intelligence (IJACI-ECAI 2026) . This time, we hear from Mayra Elwes about her work developing machine learning methods for clinical time-series data. Tell us a bit about your PhD - where are you studying, and what is the topic of your research? I am a second-year computer science PhD student at the Institute for Biomedical Informatics at the University Hospital Cologne. My research focuses on the generalisation and domain adaptation of machine learning for clinical time-series forecasting, especially for clinic-to-clinic generalization scenarios.

The US resurgence of measles is forcing hospitals and health systems to adopt new protocols and procedures to deal with a disease they thought was in the past. John Goldman had not seen a case of measles in 30 years. But since April, the infectious disease specialist with the University of Pittsburgh Medical Center in central Pennsylvania has had dozens of patients come down with the disease. "I never thought I would see this come back," he says. His health system, like others, has had to adapt to a new normal as measles makes a comeback in the United States.

The practice of editing the genes of embryos remains highly controversial and risky, but Origin Genomics founder Cathy Tie argues its a "moral imperative" to address hereditary diseases. When the Chinese scientist He Jiankui announced in 2018 that he had created the first gene-edited babies, the experiment was widely condemned as reckless and premature. It ended with He in prison. But that hasn't stopped the push for gene-edited human embryos, with biotech entrepreneur Cathy Tie arguing that doing so isn't just urgent--it's a "moral imperative." Tie is the 30-year-old founder of Origin Genomics, a company that launched in March with plans to bring gene-edited embryos to IVF clinics.

You're viewing the US edition You can switch to the UK or AU homepage at any time using this menu. Presley Gerber's'inevitable' death: Family insiders reveal life-long secret struggle that sparked'self-destruct' spiral... and mother Cindy Crawford's desperate bid to save him before shock death at 27 The ruthless rise of Bettina Trump: She takes selfies with the President and comforts'tense' Don Jr... but there are red flags her new family cannot ignore Millions across 17 US states warned to brace for surprise nor'easter in HOURS Melania makes eyebrow-raising CNN decision as Trump's media ban sparks White House chaos Ozempic made me go permanently BLIND, New England dad claims in lawsuit... before his girlfriend landed the worst blow of all A fleeting look in Patrick Clancy's eyes during his 60 Minutes interview sent shockwaves through me... this is the truth about him and his pregnant new wife that must be said: KENNEDY Trump's gloating five-word taunt to boycotting networks as he stands beside free speech crusader Mamdani Former Fox News producer Jennifer Eckhart dies by suicide at 36, six years after she accused network's former anchor Ed Henry of raping her I used to say'size doesn't matter'... until one man proved me wrong last week. Eagles legend and Super Bowl champion makes dramatic return to Philadelphia to ease team's injury woes Firebrand Rep. Lauren Boebert is spotted during her'important task' visiting Botox clinic BEFORE lashing out over claims she had sex with staffers Katy thought her painful foot was a running injury from a midlife exercise regime... but aged just 42 she was diagnosed with Parkinson's. Prince Harry'is in talks to make a documentary about Princess Diana to mark the 30th anniversary of her death' Living near a Costco warehouse store could add THOUSANDS to the value of your home - but there's a catch Rising star Democrat JB Pritzker reveals medical secret behind his dramatic 80lb weight loss... fueling 2028 ambitions My dry eyes and mouth were signs of a devastating disease that mainly strikes women. I'm urging others to seek help as doctors warn a delay can be disastrous Which midterm races should YOU be watching?

Good Connection: Uplifting stories for a digital age Creator Playbook Trending Now Say More Look Up Mashable's Best: E-readers, robovacs, laptops, earbuds, smart home and more Switch Off Mashable Voices Mashable Selects Safety Net Versus Gift Ideas For Everyone On Your List All Series'I get so upset and frustrated': What dating is like on a GLP-1 Finding a partner after weight loss might be even harder. Anna Iovine is the associate editor of features at Mashable. Previously, as the sex and relationships reporter, she covered topics ranging from dating apps to pelvic pain. Before Mashable, Anna was a social editor at VICE and freelanced for publications such as Slate and the Columbia Journalism Review. Follow her on Bluesky .

How an alliance of tech startups, MAHA operatives, and actual medical experts made millennial women the new face of hormone therapy. Lisa Schrenk didn't know it yet, as she trudged down a dirt trail last August, but her life was about to change. She'd set out late the night before with her hiking group, scrambling up Virginia's Old Rag Mountain in darkness. They reached the peak in time to watch the sun rise over the Blue Ridge range. Afterward, the women snapped photos. In one, Schrenk gazes out over the horizon, her long dark hair pulled into a ponytail. The image is deceptively triumphant. In reality, she had been contemplating suicide. Schrenk, a longtime IT specialist for the federal government, had started setting aside belongings for friends and family, organizing her financial affairs, and clearing out her office.

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You're viewing the US edition You can switch to the UK or AU homepage at any time using this menu. Dolly Parton modelled her look on the'town tramp' and never denied repeated affair rumours - but her brilliant business brain meant she could have been a billionaire if she hadn't given so much to charity What the Sussexes' new life in Britain will really look like: It's Harry's dream... Meghan will'come and go' - but it's all part of the 15-year plan. Dolly Parton's heartbreaking final year: The deaths of her beloved husband and brother, devastating health struggles... and the comeback she was forced to abandon The photos that sparked wild internet rumours: James Blunt mingles with Hayden Panettiere on a yacht in 2009 after he broke his silence on claims he was the'British singer' who the late actress was put into bed with aged 18 Dolly Parton's health woes as family reveals intimate funeral plans after country legend's death at 80: Live updates Chilling 911 call details how police watched Montana home go up in flames before 8 found dead inside... as shooting suspect's haunting final act is revealed Dolly Parton's devastating final interview just FOUR DAYS before her death: 'I still have so many things I want to achieve' Fleet of'doomsday planes' spotted over US hours after CIA boss visits Moscow Lindsay Clancy claimed she heard chilling'voice' telling her to kill her three children while she made them dinner, final witness says: Live updates My wife and I are in our 50s and haven't had sex for TWO YEARS. Today I'm revealing all about the desperate truth so many couples hide... by CHRIS TAUNTON Trump's CIA chief John Ratcliffe makes surprise trip to Moscow for secret meeting amid grim fears for Poland Menopause made my hair fall out. Then I discovered a new hair-loss solution.